Scalable oligonucleotide purification

ClarityCapture™ replaces HPLC purification with a 5-10 min membrane capture step - high purity and linearly scalable from research to the clinic.

>20x
Faster purification
39%
Lower COGS than HPLC
65%
Higher batch throughput
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The Problem

Purification is holding oligonucleotide therapies back

Packed resin beds have a practical and physical ceiling. Column pressure and solvent volumes compound at scale, making traditional chromatography the bottleneck every oligo therapy eventually faces.
Why we started GemBio
4,300kg
Waste per kg of RNA produced
>50%
Waste from purification alone
~370
RNA & oligo medicines in clinical trials
>1,300
Therapies in pre-clinical R&D
The solution

ClarityCapture™ — built for every stage of oligo development

CDMOs

Integrate ClarityCapture™ into existing synthesis workflows. Easy adoption, with no major capex required.

Pharma/Biotechs

Our purification kit aims to provide consistent and linear CMC profiles from pre-clinical through to GMP scale.

Diagnostics

High purity oligonucleotides at the volumes, turnaround times, and purity high resolution diagnostic assays demand.
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Get in touch

Interested in ClarityCapture™ for your oligo workflow?

We'd like to hear from you.

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